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‘General Hospital’ Spoilers Monday, May 16: Anna In Danger, Ava Grills Nina, Josslyn Schemes, Curtis Snaps

On the next GH, Port Charles chaos erupts as Anna Devane’s nightmare deepens, Emma Scorpio-Drake faces a personal crisis, and Isaiah Gannon suffers a violent confrontation.

'General Hospital' Spoilers Monday, May 16: Anna In Danger, Ava Grills Nina, Josslyn Schemes, Curtis SnapsGeneral Hospital spoilers for Monday, May 16 suggest some twists. For one thing, we will find out that Anna Devane (Finola Hughes) is in some deep danger.

Emma Scorpio-Drake (Braedyn Bruner) faces a crisis. Plus, Isaiah Gannon (Sawandi Wilson) gets attacked! Keep reading to find out what is coming up in the ABC soap opera.

5 Key Takeaways

  • Laura Collins fears Anna Devane is in far more danger than expected
  • Emma Scorpio-Drake turns to Felicia Scorpio for urgent help
  • Ava Jerome grows suspicious of Nina Reeves and Jack Brennan
  • Josslyn Jacks works a strategy against her captor, Cassius Faison
  • Curtis Ashford attacks Isaiah Gannon, leaving Portia furious

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Laura Collins’ Warning

Let’s start off with Anna. Fans know that Anna is still in a mental treatment center after all the things done to her in captivity.

At first, they assumed it was a real mental break because she kept mentioning Cesar Faison (Anders Hove). However, now Laura Collins (Genie Francis) realizes that Anna could be in grave danger. 

The mayor updates Dante Falconeri (Dominic Zamprogna) and Mac Scorpio (John J. York).

The mayor informs them that Anna is in greater trouble than they initially thought. 

Emma Scorpio-Drake’s Crisis

Speaking of Anna, her granddaughter is facing a crisis. Emma turns to Felicia Scorpio (Kristina Wagner) for help.

The girl says that there must be something really wrong with her

Could it be a surprise pregnancy? She has been intimate with Giovanni “Gio” Palmieri (Giovanni Mazza).

Ava Jerome Suspects

General Hospital spoilers for Monday, May 16 reveal that Ava Jerome (Maura West) will get suspicious.

The woman interrogates Nina Reeves (Cynthia Watros). In a hushed tone, Ava asks since when has Nina been so close with Jack Brennan (Chris McKenna)?

Josslyn Jacks’ Strategy

Over in captivity, Josslyn Jacks (Eden McCoy) is getting Cassius Faison aka Nathan West (Ryan Paevey) to talk.

That’s good as it can give her a lot of information.

It could also help her develop a connection or bond with her captor, which could give her a chance to escape eventually. 

In the meantime, fake Nathan says Joss isn’t going anywhere. However, the blonde says they will see about that. 

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Sonny Corinthos’ Gift

As for Gio, he gets a gift from Sonny Corinthos (Maurice Benard).

The young man is grateful and tells Sonny, “This is where you get to say, ‘I told you so.’”

Isaiah Gannon Injured

Over with Isaiah, he just got attacked by Curtis Ashford (Donnell Turner).

Of course, what did Isaiah expect when he blasted Curtis as a father?

In any case, Portia Robinson (Brook Kerr) tends to her boyfriend.

The woman also glares at Curtis and demands to know what is wrong with him.

Of course, Curtis is going to make the situation even worse, so stay tuned!

Which storyline are you looking forward to seeing the most on Monday, May 16, 2026?

Catch the popular ABC soap daily for all the exciting moments and visit CTS often for the best General Hospital updates, spoilers, and news.

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